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By F. F. Nord

Advances in Enzymology and comparable parts of Molecular Biology is a seminal sequence within the box of biochemistry, delivering researchers entry to authoritative stories of the newest discoveries in all parts of enzymology and molecular biology. those landmark volumes date again to 1941, offering an unmatched view of the ancient improvement of enzymology. The sequence bargains researchers the most recent figuring out of enzymes, their mechanisms, reactions and evolution, roles in advanced organic procedure, and their software in either the laboratory and undefined. every one quantity within the sequence beneficial properties contributions by means of top pioneers and investigators within the box from around the globe. All articles are rigorously edited to make sure thoroughness, caliber, and readability.

With its wide variety of subject matters and lengthy historic pedigree, Advances in Enzymology and comparable parts of Molecular Biology can be utilized not just via scholars and researchers in molecular biology, biochemistry, and enzymology, but in addition via any scientist drawn to the invention of an enzyme, its houses, and its purposes

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Extra resources for Advances in Enzymology and Related Areas of Molecular Biology, Volume 7

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W’ 60 z W V 5: W z 9 40 3 20 0 40 80 120 160 TIME. sec. 200 240 280 Fig. 6. Course of luminescence after adding mercuric chloride to suspensions of bacterial cells (35). seconds after the first contact to lower the luminescence of these bacteria to its final levels-from 55 to 10% for mcrcuric chloride concentrations M (Fig. 6). It seems probable that perranging from to 5 x meability to this salt (which lowers permeability) is a real factor, the reaction within the cell occurring rapidly as the salt permeates a t a relatively slow rate.

It secms more probable that the intake of potassium, as shown in Figure 8 from Pulvcr and VerzSLr, reflects the counter gradient of hydrogen ions. As fermentation proceeds and bcforc carbon dioxide is liberated, the hydrogen-ion concentration in the protoplasm rises, and with this the rate of ionic exchange rises. Although potassium is essential for maximum fermentation, there is no evidence that its permeation is normally slow enough to affect the fermentation ratr curves. In fact such experiments as those done by Brooks ( 5 ) demonitrate exceedingly rapid penetration of potassium and other cations by ionic exchange into several types of cells.

Rhythmic contractility (82) is probably a potential property of all forms of protoplasm, manifesting itself primarily in tissues where i t is needed, in heart muscle, intestines, the diaphragm, and in many unicellular organisms such as leucocytes, swimming protozoa, and myxomycetes (40). The molecular basis of contractility is now quite well understood. It is generally assumed that elastic proteins and rubber-like materials are built of flexible polypeptide chains. The similarity in the molecular mechanism of such materials is indicated by the fact that all yidd S-shaped curves.

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