Download Advanced Mechanical Models of DNA Elasticity by Yakov M Tseytlin PDF

By Yakov M Tseytlin

Advanced Mechanical types of DNA Elasticity contains assurance on 17 diverse DNA versions and the function of elasticity in organic capabilities with huge references. the unconventional complicated helicoidal version defined displays the direct connection among the molecule helix constitution and its particular homes, together with nonlinear positive factors and transitions. It presents an advent to the nation of the sphere of DNA mechanics, identified and conventional versions with their brief research, in addition to insurance on experimental equipment and information, the impact of electric, magnetic, ionic stipulations at the patience size, and dynamics with viscosity impression. It then addresses the necessity to comprehend the character of the non-linear overstretching transition of DNA below strength and why DNA has a detrimental twist-stretch coupling.

  • Includes assurance of 17 modern types of DNA mechanics with analysis
  • Provides comparability of DNA and RNA mechanical features
  • Covers advances in experimental options together with AFM, X-ray, and optical tweezers
  • Contains wide references for extra reading

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Extra resources for Advanced Mechanical Models of DNA Elasticity

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2013. Functional helicoidal model of DNA molecule with elastic nonlinearity. AIP Adv. 3, 062110. , 2014. DNA molecule elastic nonlinearity: a functional helicoidal model. ZAMM 94 (6), 505–508. , 2012. Extreme bendability of DNA less than 100 base pairs long revealed by single-molecule cyclization. Science 337 (6096), 1097. , 2013. Strong bending of the DNA double helix. Nucleic Acids Res. 41 (14), 6785–6792. , 2013, Kratky-Porod model. University of Split, Faculty of math and natural science.

The noise level is less than 1 pN. The trapping occurs due to a balance between optical radiation pressure and the direction of the intensity gradient in the focused field. The vertical trap maintains all of the advantages of AFM, but adds the ability to apply very low forces to the sample. 1 The Radiation Pressure of Light Relations. 1) 42 Advanced Mechanical Models of DNA Elasticity where  = 2πħn0νlgt is the mean value of the spatial density of incidence light, Rref is the coefficient of light reflection, i is the incident angle of light on the flat surface, n0 is the concentration of photons in incidence light, 2πħ is cn Planck’s constant, and ν lgt = ref ⋅i is the frequency of light in a medium.

Ten years of tension: single-molecule DNA mechanics. Nature 421, 423–427. , 2012. Atomistic to continuum modeling of DNA molecules. In: Advances in Soft Matter Mechanics. Springer, Berlin, Heidelberg, (Chapter 1). , 1997. Modeling extreme extension of DNA. Biopolymers 42, 383–385. , 2000. Mechanical stability of single DNA molecules. Biophis. J. 78, 1997–2007. , 2004. Overstretching and force-driven strand separation of double-helix DNA. Phys. Rev. E 70, 011910. , 2005. The role of nucleoid-associated proteins in the organization and compaction of bacterial chromatin.

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